It is my impression that when the "author determined" biological
assembly (REMARK 350) specifies the same structure as the asymmetric
unit, sometimes the authors simply forgot to specify a known assembly
during PDB deposition. Does anyone know of PDB entries where this has occurred?
Thanks, Eric
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Eric Martz, Professor Emeritus, Dept Microbiology
U Mass, Amherst -- http://Martz.MolviZ.Org
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Hi Eric
Here are a few cases for which the REMARK 350 annotated by authors says
the protein is a monomer but the authors in the paper say that the
proteins are actually dimers and prove it with independent experimental
methods (like AUC, gel filtration or light scattering):
3pc4
1wxi
1w3u
2ex2
2fwv
1mdo
1ytq
1v2x
Thus my guess is that these cases are most likely authors annotating a
monomer by default, since the asymmetric unit is monomeric.
Hope it helps
Jose
Jose Duarte
Laboratory of Biomolecular Research
Paul Scherrer Institute
5232 Villigen PSI
Switzerland
http://www.psi.ch/lbr/capitani_-guido
On 06/13/2013 10:39 PM, Eric Martz wrote:
It is my impression that when the "author determined" biological
assembly (REMARK 350) specifies the same structure as the asymmetric
unit, sometimes the authors simply forgot to specify a known assembly
during PDB deposition. Does anyone know of PDB entries where this has occurred?
Thanks, Eric
/* - - - - - - - - - - - - - - - - - - - - - - - - - - -
Eric Martz, Professor Emeritus, Dept Microbiology
U Mass, Amherst -- http://Martz.MolviZ.Org
Top Five 3D MolVis Technologies http://Top5.MolviZ.Org
FirstGlance: 3D Views in Nature Structure - http://firstglance.jmol.org
3D Wiki with Scene-Authoring Tools http://Proteopedia.Org
Biochem 3D Education Resources http://MolviZ.org
ConSurf - Find Conserved Patches in Proteins: http://consurf.tau.ac.il
Atlas of Macromolecules: http://atlas.molviz.org
Interactive Molecules in Public Spaces http://MolecularPlayground.Org
Workshops: http://workshops.molviz.org
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