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Coronavirus mutations in interactive 3D

Eric Martz

Wed, Dec 23, 2020 9:11 PM

See the locations of the 4 most concerning mutations on a rotating 3D
model of spike protein with interpretations of their likely consequences
at this article posted December 22, 2020:

https://urldefense.com/v3/http://proteopedia.org/w/SARS-CoV-2_spike_protein_mutations;!!Mih3wA!SGoZpg-CuqEL91L40B0z3YnPH3tj0iK00XFCAOg49MGBZ17FhMfDidim3odnav8$

The article is written to be suitable for high-school students. There
are links to additional background material as well as references to
reliable scientific publications and news sources.

The article offers a downloadable movie of the spike protein, slide
presentation-ready, showing the conformational change when it is primed,
with the locations of mutations indicated.

-Eric Martz

Coronavirus mutations reported within the past week by scientists in the UK have raised concern about an increased transmission rate of COVID-19. The report even temporarily closed the borders between the UK, France, and other EU countries, causing huge backups of trucking and supply concerns. See the locations of the 4 most concerning mutations on a rotating 3D model of spike protein with interpretations of their likely consequences at this article posted December 22, 2020: https://urldefense.com/v3/__http://proteopedia.org/w/SARS-CoV-2_spike_protein_mutations__;!!Mih3wA!SGoZpg-CuqEL91L40B0z3YnPH3tj0iK00XFCAOg49MGBZ17FhMfDidim3odnav8$ The article is written to be suitable for high-school students. There are links to additional background material as well as references to reliable scientific publications and news sources. The article offers a downloadable movie of the spike protein, slide presentation-ready, showing the conformational change when it is primed, with the locations of mutations indicated. -Eric Martz Professor Emeritus, Dept Microbiology (he/him/his) University of Massachusetts, Amherst MA US Martz.MolviZ.Org <https://urldefense.com/v3/__http://martz.molviz.org/__;!!Mih3wA!SGoZpg-CuqEL91L40B0z3YnPH3tj0iK00XFCAOg49MGBZ17FhMfDidimrt7i3mM$ >

Bernhard Rupp

Wed, Dec 23, 2020 10:18 PM

"lineages are already spreading in many countries around the world -- whether they were imported or arose semi-independently"

I guess the connection to the trucks lends a completely new meaning to the adjective 'semi-independent' 😊

Cheers, BR

-----Original Message-----
From: pdb-l-bounces@sdsc.edu pdb-l-bounces@sdsc.edu On Behalf Of Eric Martz
Sent: Wednesday, December 23, 2020 13:11
To: g.pdb pdb-l@sdsc.edu
Subject: pdb-l: Coronavirus mutations in interactive 3D

See the locations of the 4 most concerning mutations on a rotating 3D model of spike protein with interpretations of their likely consequences at this article posted December 22, 2020:

https://urldefense.com/v3/http://proteopedia.org/w/SARS-CoV-2_spike_protein_mutations;!!Mih3wA!SGoZpg-CuqEL91L40B0z3YnPH3tj0iK00XFCAOg49MGBZ17FhMfDidim3odnav8$

The article is written to be suitable for high-school students. There are links to additional background material as well as references to reliable scientific publications and news sources.

The article offers a downloadable movie of the spike protein, slide presentation-ready, showing the conformational change when it is primed, with the locations of mutations indicated.

-Eric Martz

Professor Emeritus, Dept Microbiology (he/him/his) University of Massachusetts, Amherst MA US Martz.MolviZ.Org <https://urldefense.com/v3/http://martz.molviz.org/;!!Mih3wA!SGoZpg-CuqEL91L40B0z3YnPH3tj0iK00XFCAOg49MGBZ17FhMfDidimrt7i3mM$ > TO UNSUBSCRIBE OR CHANGE YOUR SUBSCRIPTION OPTIONS, please see https://lists.sdsc.edu/mailman/listinfo/pdb-l .

"lineages are already spreading in many countries around the world -- whether they were imported or arose semi-independently" I guess the connection to the trucks lends a completely new meaning to the adjective 'semi-independent' 😊 Cheers, BR -----Original Message----- From: pdb-l-bounces@sdsc.edu <pdb-l-bounces@sdsc.edu> On Behalf Of Eric Martz Sent: Wednesday, December 23, 2020 13:11 To: g.pdb <pdb-l@sdsc.edu> Subject: pdb-l: Coronavirus mutations in interactive 3D Coronavirus mutations reported within the past week by scientists in the UK have raised concern about an increased transmission rate of COVID-19. The report even temporarily closed the borders between the UK, France, and other EU countries, causing huge backups of trucking and supply concerns. See the locations of the 4 most concerning mutations on a rotating 3D model of spike protein with interpretations of their likely consequences at this article posted December 22, 2020: https://urldefense.com/v3/__http://proteopedia.org/w/SARS-CoV-2_spike_protein_mutations__;!!Mih3wA!SGoZpg-CuqEL91L40B0z3YnPH3tj0iK00XFCAOg49MGBZ17FhMfDidim3odnav8$ The article is written to be suitable for high-school students. There are links to additional background material as well as references to reliable scientific publications and news sources. The article offers a downloadable movie of the spike protein, slide presentation-ready, showing the conformational change when it is primed, with the locations of mutations indicated. -Eric Martz Professor Emeritus, Dept Microbiology (he/him/his) University of Massachusetts, Amherst MA US Martz.MolviZ.Org <https://urldefense.com/v3/__http://martz.molviz.org/__;!!Mih3wA!SGoZpg-CuqEL91L40B0z3YnPH3tj0iK00XFCAOg49MGBZ17FhMfDidimrt7i3mM$ > TO UNSUBSCRIBE OR CHANGE YOUR SUBSCRIPTION OPTIONS, please see https://lists.sdsc.edu/mailman/listinfo/pdb-l .